Open Access Open Access  Restricted Access Subscription or Fee Access

The parenteral opioid shortage: Causes and solutions

Hanna Hollingsworth, PharmD, Chris Herndon, PharmD, CPE

Abstract


-

Keywords


Opioids, shortage, protocol, ketamine, nalbuphine, butorphanol

Full Text:

PDF

References


FDA: FDA Drug Shortages. Available at https://www.accessdata.fda.gov/scripts/drugshortages/. Accessed February 7, 2018.

Section 826 of Title 21 United States Code Controlled Substances Act. Available at: https://www.deadiversion.usdoj.gov/21cfr/21usc/826.htm. Accessed February 7, 2018.

Office USGA. GAO-15-202, DRUG SHORTAGES: Better Management of the Quota Process for Controlled Substances Needed; Coordination between DEA and FDA Should Be Improved. 2015. Available at https://www.gao.gov/assets/670/668252.pdf. Accessed February 7, 2018.

Woodcock J, Wosinska M: Economic and technological drivers of generic sterile injectable drug shortages. Clin Pharmacol Ther. 2013; 93(2): 170-176. doi:10.1038/clpt.2012.220

FDA: 2017-Hospira Inc 2/14/17. Available at: https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm542587.htm. Accessed February 7, 2018.

Galinski M, Dolveck F, Combes X, et al.: Management of severe acute pain in emergency settings: Ketamine reduces morphine consumption. Am J Emerg Med. 2007; 25(4): 385-390. doi:10.1016/j.ajem.2006.11.016

Barash PG: Clinical Anesthesia. Available at: https://books.google.com/books?id=exygUxEuxnIC&dq=Clinical+Anesthesia,+7e+barash+butorphanol&source=gbs_navlinks_s. Accessed February 7, 2018.

Beaudoin FL, Lin C, Guan W, et al.: Low-dose Ketamine Improves Pain Relief in Patients Receiving Intravenous Opioids for Acute Pain in the Emergency Department: Results of a Randomized, Double-blind, Clinical Trial. Acad Emerg Med. 2014; 21(11): 1194-1202. doi:10.1111/acem.12510

Green SM, Roback MG, Kennedy RM, et al.: Clinical practice guideline for emergency department ketamine dissociative sedation: 2011 update. Ann Emerg Med. 2011; 57(5): 449-461. doi:10.1016/j.annemergmed.2010.11.030

Pharmacist’s Letter: Equianalgesic Dosing of Opioids for Pain Management. Available at: http://pharmacistsletter.therapeuticresearch.com/pl/ArticleDD.aspx?nidchk=1&cs=&s=PL&pt=2&segment=4662&dd=280821. Published 2015. Accessed February 7, 2018.




DOI: http://dx.doi.org/10.5055/jom.2018.0434

Refbacks

  • There are currently no refbacks.
This site uses cookies to maintain session information critical to the user's experience and environment on this system. Click "Accept Cookies" to continue.
For more details please visit our privacy statement at: Privacy & GDPR