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A mentally stimulating activities program for the treatment of neuropsychiatric symptoms in Alzheimer’s disease

Angie L. Sardina, PhD, Suzanne Fitzsimmons, MSN, ARNP, GNP, Catherine M. Hoyt, BA, Linda L. Buettner, PhD

Abstract


This study evaluated whether a mentally stimulating activities (MSA) program reduced neuropsychiatric symptoms and improved cognitive status and quality of life, as compared to a support group for persons in the early stage of Alzheimer’s disease (AD). This randomized controlled trial included 81 adults (aged 55+), who were randomly assigned to the MSA group (treatment) or a social support group (control). A repeated measures multivariate analysis of variance (MANOVA) identified that MSA participants significantly reduced apathy (p < 0.001) and depressive symptoms (p < 0.001), as well as improved cognitive status (p < 0.001) and quality of life (p < 0.001) as compared to the control group. A structured classroom-style MSA program may be a viable and therapeutic intervention to alleviate neuropsychiatric symptoms, and improve cognitive status and quality of life in early-stage AD.


Keywords


mentally stimulating activities, support groups, apathy, Alzheimer’s disease, Depression

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References


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DOI: https://doi.org/10.5055/ajrt.2019.0200

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