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Facilitating discontinuation of intravenous opioids by concurrent use of sublingual buprenorphine with rapid microdosing induction: A pain management case study

Arjun Tara, DO, Gregory Acampora, MD, Jingping Wang, MD, PhD, Karina De Sousa, BS, Yi Zhang, MD, PhD


We report a case in which sublingual buprenorphine was used to help transition a patient off intravenous (IV) opioid analgesics medications post-multiple abdominal procedures. Intravenous opioids are commonly used in inpatient surgical pain management for patients with severe pain who are unable to take oral medications. Typically, a short course of IV analgesics is used, followed by transition to oral analgesic regimen. However, in patients with poor gastrointestinal absorption, pain control can be challenging. We present this case to highlight how sublingual buprenorphine can be a useful agent for acute pain management, especially when conventional strategies provide suboptimal responses.


buprenorphine, sublingual buprenorphine, acute pain management, perioperative pain management, microdosing induction

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