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Table of Contents

Articles

Balancing opioid-induced gastrointestinal side effects with pain management: Insights from the online community Cynthia B. Whitman, MPH, Mark W. Reid, PhD, Corey Arnold, PhD, Lyann Ursos, PhD, Roee Sa’adon, MS, Jonathan Pourmorady, MD, Brennan M. R. Spiegel, MD, MSHS, Haridarshan Patel, PharmD

PDF 383-391

Tolerability and efficacy of tapentadol extended release in elderly patients ≥75 years of age with chronic osteoarthritis knee or low back pain David M. Biondi, DO, Jim Xiang, PhD, Mila Etropolski, MD, Bruce Moskovitz, MD

PDF 393-403

A pharmacokinetic evaluation of single and multiple doses of extended-release hydrocodone bitartrate in subjects experiencing surgical or osteoarthritic pain Cynthia Y. Robinson, PhD, Christopher M. Rubino, PharmD, Stephen J. Farr, PhD

PDF 405-415

Relationship between change in pain intensity and functional outcomes in patients with chronic pain receiving twice daily extended-release hydrocodone bitartrate Charles Argoff, MD, Paul Arnstein, RN, PhD, FAAN, Steven Stanos, DO, Cynthia Y. Robinson, PhD, Bradley S. Galer, MD, Errol Gould, PhD, Arnold Gammaitoni, PharmD

PDF 417-424

Twelve-month, open-label assessment of long-term safety and abuse potential of hydrocodone extended-release formulated with abuse-deterrence technology in patients with chronic pain Martin E. Hale, MD, Thomas R. Zimmerman, Jr, MD, Yuju Ma, MS, Richard Malamut, MD

PDF 425-434

Assessment of the use of oral fluid as a matrix for drug monitoring in patients undergoing treatment for opioid addiction Frank Kunkel, MD, Elizabeth Fey, MS, Damon Borg, PhD, Richard Stripp, PhD, Christine Getto, BS

PDF 434-442

Case Studies

Opioid rotation: A case example using methadone in spinal cord injury Jayne Pawasauskas, PharmD, BCPS

PDF 443-448

Furosemide as a potential unintended urine drug screen confounder during methadone maintenance treatment Rachel L. Bauer, PharmD, Wesley L. Geminn, PharmD, Jason A. Carter, PharmD

PDF 449-452